Lale (Ece Uslu), a paediatrician, faces her worst nightmare when diagnosed with a terminal brain tumour. As she prepares for the end, she seeks a new mother for her children. At the same time, Zeynep (Burcu Kara), a kindergarten teacher grappling with infertility and a broken marriage, finds her path crossing with Lale’s. “Lale’s Last Wish” follows Lale’s fight for life and her search for a guardian for her daughters, intertwined with Zeynep’s journey to find solace and purpose.